Customizable advanced fluorescence microscopy platform

Marianas incorporates advanced optics, cameras, computers and proprietary electronics to achieve unparalleled speed, precision and flexibility in live cell image acquisition. Innovative SlideBook software works seamlessly within Marianas for powerful and intuitive image acquisition and analysis. An ever-growing lineup of 3i technologies and our team of experienced scientists and programmers ensure that Marianas is always a step above the rest.

The Marianas platform is equipped for both live and fixed cell widefield epifluorescence applications as well as transmitted illumination techniques.

 

Common uses include:

 

•  Timelapse

 

•  3D deconvolution

 

•  Large format montage

 

•  Ratiometric imaging

 

•  Multidimensional imaging (6D applications)

 

•  FRET

 

•  Stereology
MDCK cell line stained for DNA, alpha-tubulin and E-cadherin
Pellman lab, Dana-Farber Cancer Institute and Harvard Medical School

Advanced options

Advanced options further expand the capabilities of this system to address a wide variety of applications.
•  Spinning Disk Confocal

 

•  FRAP

 

•  Rapid 4D

 

•  Photoactivation and uncaging

 

•  TIRF

 

•  FLIM

 

•  Single molecule studies

 

•  Real-time deconvolution

 

•  Environmental control

 

•  Simultaneous dual camera acquisition and synchronization with electrophysiology and automated perfusion systems.
Pancreatic Islet Cell

Customize your system

CORE COMPONENTS

Research Inverted
Microscope

Fully motorized and capable
of autofocus and
all
advanced techniques, with
a full suite of world class
objectives and filters.

LED Light Source

High power 6-channel
LED light source.

XYZ Stage

Fully motorized
multi-specimen platform
with options for linear
encoder sensitivity and
piezo z focus.

Computer

Dell professional grade
workstations offer
best-in-class speed and
large dataset handling.

Cameras

sCMOS, EMCCD and
intensified EMCCD options
for high resolution,
low light sensitivity and
frequency domain FLIM.

SlideBook 6

SlideBook offers advanced
acquisition via control of
hundreds of devices, in addition
to advanced analytical
techniques and 3D rendering.

ADVANCED TECHNOLOGIES

Spinning Disk Confocal

Yokogawa high speed CSU-X1
and wide field-of-view
CSU-W1 offer sensitive and
flexible 3D imaging solutions
for live cell microscopy.

LaserStack + FiberSwitcher

Modular solid state laser launch
with <1ms changing between
SDC, TIRF and Photomanipulation.

Frequency Domain FLIM

Modulated lasers and
ICCD camera allow for
video rate FLIM with high
spatial resolution.

TTL Synchronization

Custom TTL electronics
available in rack-mounted and
compact USB form factors.

VectorTIRF

VectorTIRF provides motorized
X,Y TIRF illumination

Incubator

Full enclosure with
temperature controller, heater
and CO2 gas mixer.

MULTI-MODAL CAPABILITIES

mSwitcher

Millisecond fast optical
path selection between
3 devices and microscope.

mSAC

High speed spherical
aberration correction as
3D data is collected.

Bifurcator

Spectral separation
or combination in a
perfect image relay.

Optimizer

Optimal positioning of
emission filter wheels in a
collimated infinity space.

PHOTOMANIPULATION

Vector

Diffraction limited high speed
X,Y scanner for line and
ROI interest scanning of
laser-based photomanipulation
light sources.

Phasor

Digital holography pattern
photomanipulation in X,Y and Z
without intensity loss.

Ablate

Laser ablation system with
532nm pulsed laser.

Specifications

LOREM IPSUM

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LOREM IPSUM

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Find out more
about Marianas






SALES

Phone: +1 (303)-607-9429 x1
Email: sales@intelligent-imaging.com

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SUPPORT

Phone: +1 (303)-607-9429 x2
Email: support@intelligent-imaging.com

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