Image courtesy of Dr. Doncic Lab, University of Texas Southwestern Medical Center.
LightSheet
From single molecules to whole organisms, 3i LightSheet systems enable live cell imaging beyond the limitations of traditional confocal modalities
Ultrathin light sheet for rapid acquisition with minimal photodamage and extremely efficient illumination
HeLa cells transfected with GFP-Lifeact (488nm) to visualize actin dynamics and stained with DiL (561nm red)(Thermo) to visualize membrane dynamics
Courtesy James Springfield, Institute for Molecular Bioscience (IMB) at the University of Queensland
Smooth muscle cells in the arteries from veins and capillaries of cleared mouse brain reported by NG2BacDsRed.
Sample courtesy of Dr. Woo-Ping Ge, University of Texas Southwestern Medical Center. Cleared with PEGASOS, imaged on Cleared Tissue LightSheet (CTLS), and rendered with Aivia.
Microglia
Courtesy of Dr. S. Okabe & Dr. S. Tanaka, Department of Cellular Neurobiology, University of Tokyo
Widefield, Confocal, Multiphoton, and TIRF
Bespoke multimodal microscope systems with any combination of multiphoton, spinning disk confocal, structured illumination, spinning TIRF, photomanipulation, computer-generated holography, and more
Differentiation of oligodendrocyte from adult mouse neural stem/neural progenitor cells.
Image courtesy of Roberta Diaz Brinton, PhD lab, USC
Mouse lung imaged with VIVO and widefield illumination. Green = leukocytes.
Image courtesy of Dr. Christophe Dubois, Faculté de Pharmacie de Marseille.
A z-stack projection of ciliated cerebrospinal fluid-contacting neurons (magenta) contacting the central canal in the spinal cord of a larval zebrafish. Cilia are labeled in green.